Association of Genetic Variants of KCNJ11 and KCNQ1 Genes with Risk of Type 2 Diabetes Mellitus (T2DM) in the Indian Population: A Case-Control Study

Table 3

Genotypic and allelic distribution and association analysis of KCNQ1 rs2237895 genes polymorphism and risk of T2DM under different genetic models.

Genotype		Cases (n = 300)	Control (n = 100)	Odds ratio (95% CI)	value
AA		90 (30%)	50 (50%)	Ref	Ref
AC		153 (51%)	36 (36%)	2.36 (1.43–3.89)	0.0007
CC		57 (19%)	14 (14%)	2.26 (1.14–4.46)	0.017
value −0.001
Recessive model	CC	57	14	1.44 (0.76–2.71)	0.259
	AC + AA	243	86
Dominant model	AC + CC	210	50	2.33 (1.46–3.70)	0.0003
	AA	90	50
Codominant model	AC	153	36	1.85 (1.16–2.95)	0.009
	AA + CC	147	64
Allele
A		336 (56%)	136 (68%)	1.66 (1.19 to 2.34)	0.003
C		264 (44%)	64 (32%)