Research Article
Association of Genetic Variants of KCNJ11 and KCNQ1 Genes with Risk of Type 2 Diabetes Mellitus (T2DM) in the Indian Population: A Case-Control Study
Table 5
Clinicopathological characteristics of T2DM patients between wild and carrier of a variant allele of the KCNJ11 gene.
| Characteristic | Total | Wild (AA) | Carrier (AG + GG) | value |
| Age | | | | | ≤45 | 183 | 77 | 106 | 0.358 | >45 | 117 | 43 | 74 | |
| Gender | | | | | Male | 177 | 84 | 93 | 0.0015 | Female | 123 | 36 | 87 | |
| Family history | | | | | Yes | 131 | 49 | 82 | 0.419 | No | 169 | 71 | 98 | |
| Smoking | | | | | Yes | 139 | 59 | 80 | 0.421 | No | 161 | 68 | 100 | |
| Alcohol consumption | | | | | Yes | 140 | 62 | 78 | 0.156 | No | 160 | 5 | 102 | |
| BMI | | | | | ≤25 | 86 | 34 | 52 | 0.916 | >25 | 214 | 83 | 128 | |
| FPG | | | | | ≤140 | 214 | 87 | 127 | 0.715 | >140 | 86 | 3 | 53 | |
| PPG | | | | | ≤208 | 171 | 77 | 94 | 0.040 | >208 | 129 | 43 | 86 | |
| HBA1C | | | | | ≤7 | 192 | 75 | 117 | 0.658 | >7 | 108 | 45 | 63 | |
| Systolic BP | | | | | ≤146 | 128 | 46 | 82 | 0.215 | >146 | 172 | 74 | 98 | |
| Diastolic BP | | | | | ≤102 | 206 | 90 | 116 | 0.053 | >102 | 94 | 30 | 64 | |
| Cholesterol | | | | | ≤245 | 192 | 84 | 108 | 0.077 | >245 | 108 | 36 | 72 | |
| FPI | | | | | ≤9 | 135 | 52 | 83 | 0.635 | >9 | 165 | 68 | 97 | |
| Triglyceride | | | | | ≤355 | 156 | 66 | 90 | 0.395 | >355 | 144 | 54 | 90 | |
| HDL-C | | | | | ≤45 | 189 | 77 | 112 | 0.732 | >45 | 111 | 43 | 68 | |
| LDL-C | | | | | ≤194 | 93 | 39 | 54 | 0.646 | >194 | 207 | 81 | 126 | |
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values were determined by the chi-square test. Significant association at . |