Research Article
Association of Genetic Variants of KCNJ11 and KCNQ1 Genes with Risk of Type 2 Diabetes Mellitus (T2DM) in the Indian Population: A Case-Control Study
Table 6
Clinicopathological characteristics of T2DM patients between wild and carrier of a variant allele of the KCNQ1 gene.
| Characteristic | Total | Wild (AA) | Carrier (AC + CC) | value |
| Age | | | | | ≤45 | 183 | 56 | 127 | 0.77 | >45 | 117 | 34 | 83 | |
| Gender | | | | | Male | 177 | 59 | 118 | 0.130 | Female | 123 | 31 | 92 | |
| Family history | | | | | Yes | 131 | 39 | 92 | 0.939 | No | 169 | 51 | 118 | |
| Smoking | | | | | Yes | 139 | 42 | 97 | 0.939 | No | 161 | 48 | 113 | |
| Alcohol consumption | | | | | Yes | 140 | 45 | 95 | 0.448 | No | 160 | 45 | 115 | |
| BMI | | | | | ≤25 | 86 | 27 | 59 | 0.738 | >25 | 214 | 63 | 151 | |
| FPG | | | | | ≤140 | 214 | 64 | 150 | 0.955 | >140 | 86 | 26 | 60 | |
| PPG | | | | | ≤208 | 171 | 50 | 121 | 0.740 | >208 | 129 | 40 | 89 | |
| HBA1C | | | | | ≤7 | 192 | 62 | 130 | 0.248 | >7 | 108 | 28 | 80 | |
| Systolic BP | | | | | ≤146 | 128 | 33 | 95 | 0.168 | >146 | 172 | 57 | 115 | |
| Diastolic BP | | | | | ≤102 | 206 | 62 | 144 | 0.956 | >102 | 94 | 28 | 66 | |
| Cholesterol | | | | | ≤245 | 192 | 63 | 129 | 0.156 | >245 | 108 | 27 | 81 | |
| FPI | | | | | ≤9 | 135 | 42 | 93 | 0.704 | >9 | 165 | 48 | 117 | |
| Triglyceride | | | | | ≤355 | 156 | 36 | 120 | 0.006 | >355 | 144 | 54 | 90 | |
| HDL-C | | | | | ≤45 | 189 | 57 | 132 | 0.937 | >45 | 111 | 33 | 78 | |
| LDL-C | | | | | ≤194 | 93 | 29 | 64 | 0.764 | >194 | 207 | 61 | 146 | |
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values were determined by the chi-square test. Significant association at . |