Effects of 24 Weeks of Growth Hormone Treatment on Bone Microstructure and Volumetric Bone Density in Patients with Childhood-Onset Adult GH Deficiency
Table 1
Anthropometric characteristics of nine patients at baseline and after 24 weeks’ treatment.
Baseline
24-week follow-up
Changes
value
Height (cm)
161.9 ± 9.0
162.6 ± 9.2
0.00 (0, 2.00)
0.050
Weight (kg)
68.5 ± 15.8
71.5 ± 17.3
2.92 ± 2.52
0.008
Waist circumference (cm)
95.5 ± 11.0
94.0 ± 12.4
−1.49 ± 2.90
0.162
Hip circumference (cm)
97.9 ± 10.5
98.4 ± 11.2
2.00 (−9.00, 4.00)
0.711
Waist-hip ratio
0.97 ± 0.04
0.95 ± 0.06
−0.19 ± 0.48
0.272
FM (kg)
18.8 ± 10.3
16.3 ± 9.8
−2.44 ± 1.29
0.013
FM (%)
31.6 ± 10.0
29.1 ± 10.0
−4.72 ± 2.83
0.043
FFM (kg)
42.7 ± 8.8
45.4 ± 8.8
4.28 ± 4.00
0.156
TBW (kg)
31.3 ± 6.4
33.2 ± 6.4
3.14 ± 2.95
0.160
BMI (kg/m2)
25.8 ± 4.4
26.6 ± 4.9
1.30 (−0.80, 1.50)
0.014
FMI (kg/m2)
7.2 ± 3.3
6.2 ± 3.2
−0.10 ± 0.51
0.012
FFMI (kg/m2)
17.3 ± 2.0
18.8 ± 2.6
1.50 ± 1.35
0.068
Grip strength of nondominant hand (kg)
31.9 ± 12.2
29.1 ± 14.4
0.84 ± 6.90
0.757
Data are presented as mean ± SD or median and ranges. FM, fat mass; FFM, fat-free mass; TBW, total body water; BMI, body mass index; FMI, fat mass index; FFMI, fat-free mass index.
