Effects of Monthly Intramuscular High-Dose Vitamin D2 on Serum 25-Hydroxyvitamin D and Immune Parameters in Very Elderly Chinese Patients with Vitamin D Deficiency

Table 2

Changes in serum levels of 25(OH)D2, 25(OH)D3, iPTH, BTMs, and biochemical parameters after intervention.

Parameters	Baseline	End of intervention	t
25(OH)D, ng/mL	10.42 ± 2.79	34.36 ± 4.63	−21.227	≤0.001
25(OH)D2, ng/mL	0.69 ± 1.51	29.07 ± 5.68	−26.898	≤0.001
25(OH)D3, ng/mL	9.82 ± 2.75	5.30 ± 3.09	6.488	≤0.001
iPTH, pg/mL	37.59 ± 20.65	37.12 ± 21.46	0.245	0.808
Beta-CTx, ng/mL	0.38 ± 0.21	0.35 ± 0.20	1.014	0.320
P1NP, ng/mL	38.21 ± 17.53	37.79 ± 20.82	0.124	0.902
OC, ng/mL	12.91 ± 5.32	12.23 ± 5.27	1.395	0.175
Calcium, mmol/L	2.30 ± 0.14	2.34 ± 0.11	−1.908	0.068
Phosphorus, mmol/L	0.94 ± 0.14	0.93 ± 0.14	0.580	0.567
Urea nitrogen, μmol/L	7.98 ± 2.51	7.90 ± 2.88	0.204	0.840
Creatinine, μmol/L	97.38 ± 18.08	101.12 ± 20.39	−1.534	0.138
Total bilirubin, μmol/L	10.21 ± 5.88	10.89 ± 7.20	−1.226	0.232
AST, IU/L	17.77 ± 10.01	17.15 ± 9.93	0.324	0.749
ALT, IU/L	21.23 ± 6.16	21.81 ± 8.64	−0.423	0.676
GGT, IU/L	29.31 ± 8.62	29.38 ± 6.79	−0.027	0.979