The Association of Thyroid Hormone Changes with Inflammatory Status and Prognosis in COVID-19

Table 4

Characteristics and laboratory parameters of patients admitted to ICU.

Parameter	n	Median (min-max)	IQR	value
Age				<0.001
Admitted to ICU	31	68 (42–90)	18
Not admitted to ICU	174	55.5 (21–94)	18
Length of hospitalization				<0.001
Admitted to ICU	31	26 (7–116)	28
Not admitted to ICU	174	9 (2–40)	7
Lymphocyte percent
Admitted to ICU	31	12.5 (3.3–39.1)	8.5
Not admitted to ICU	174	20.55 (3.6–51.6)	15.5	<0.001
Neutrophil count (×10^3/μl)
Admitted to ICU	31	5.2 (1.4–21.3)	5.2
Not admitted to ICU	174	3.5 (0.9–18.2)	2.2	<0.001
Thrombocyte count (×10^3/μL)
Admitted to ICU	31	171 (89–562)	128
Not admitted to ICU	174	186.5 (36–562)	81	0.92
Ferritin (μg/L)
Admitted to ICU	31	241 (11–2770)	634
Not admitted to ICU	168	147.8 (5.3–2338)	315.6	0.02
LDH (U/L)
Admitted to ICU	31	320 (131–744)	207
Not admitted to ICU	173	257 (126–979)	122	<0.001
CRP (mg/L)
Admitted to ICU	31	75.3 (4.58–317)	82.7
Not admitted to ICU	174	25.5 (1–289)	65	<0.001
Procalcitonin (μg/L)
Admitted to ICU	31	0.13 (0.3–20.5)	0.06
Not admitted to ICU	169	0.07 (0.02–2.47)	0.07	<0.001
D-dimer (mg/L)
Admitted to ICU	31	1.58 (0.38–20)	1.59
Not admitted to ICU	173	0.59 (0.15–3.84)	0.55	<0.001
TSH (mU/L)
Admitted to ICU	31	0.82 (0.08–2.46)	0.77
Not admitted to ICU	174	1.25 (0.09–6.26)	1.38	0.005
FT4 (ng/dL)
Admitted to ICU	31	1.11 (0.61–1.67)	0.49
Not admitted to ICU	170	0.97(0.46–1.84)	0.26	0.12
FT3 (ng/L)
Admitted to ICU	31	2.06 (1.01–5.3)	1.03
Not admitted to ICU	169	2.58 (0.23–4.49)	0.7	<0.001

ICU: intensive care unit; LDH: lactate dehydrogenase; CRP: C-reactive protein; LDH: lactate dehydrogenase; TSH: thyroid-stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; IQR: interquartile range.