The Beta-Cell Function and Glucose Profile of Newly Diagnosed Acromegalic Patients with Normal Glucose Tolerance
Table 2
The insulin sensitivity and beta-cell function of newly diagnosed acromegalic patients.
Acromegaly
Control
HOMA-beta
159.77 (139.51–294.86)
117.96 (98.43–220.97)
0.172
HOMA-IR
2.95 (2.76–5.35)
2.36 (1.31–3.15)
0.059
BG0/INS0
0.39 (0.23–0.43)
0.52 (0.36–0.76)
0.103
HOMA-beta × (BG0/INS0)
61.18 (58.89–68.44)
74.06 (61.17–82.65)
0.114
(INS30 − INS0)/(BG30 − BG0)
26.51 (16.54–71.40)
22.50 (14.90–42.57)
0.674
AUCINS/AUCBG
11.23 (8.90–24.02)
7.07 (5.56–10.99)
0.074
ISOGTT
50.25 (34.76–69.50)
104.63 (67.14–129.58)
0.012
ISSI2
551.32 (520.87–684.55)
716.12 (588.83–779.83)
0.046
Data are medians (25th–75th percentile). AUCBG: area under the glucose curve; AUCINS: area under the insulin curve; AUCINS/AUCBG: insulin secretion index; ISOGTT: insulin sensitivity after glucose load; ISSI2: insulin secretion-sensitivity index-2.
