Research Article

Morning Serum Cortisol as a Predictor for the HPA Axis Recovery in Cushing’s Disease

Table 3

Diagnostic efficacy of MSC for the recovery of HPA axis.

ParametersCutoff of MSC (μg/dl)
>6.25>4.18>10.74

Sensitivity, % (95% CI)85.19 (66.3–95.8)100 (87.2–100)18.52 (6.3–38.1)
Specificity, % (95% CI)47.62 (32.0–63.3)11.9 (4.0–25.6)100 (91.6–100)
+LR (95% CI)1.63 (1.2–2.3)1.14 (1.0–1.3)
−LR (95% CI)0.31 (0.1–0.8)0.81 (0.7–1.0)
+PV (95% CI)51.1 (42.9–59.2)42.2 (39.5–44.9)100
−PV (95% CI)83.3 (65.7–92.9)10065.6 (61.5–69.6)

MSC, morning serum cortisol; +LR, positive likelihood ratio; −LR, negative likelihood ratio; +PV, positive predictive value; −PV, negative predictive value.