Research Article
Morning Serum Cortisol as a Predictor for the HPA Axis Recovery in Cushing’s Disease
Table 3
Diagnostic efficacy of MSC for the recovery of HPA axis.
| Parameters | Cutoff of MSC (μg/dl) | >6.25 | >4.18 | >10.74 |
| Sensitivity, % (95% CI) | 85.19 (66.3–95.8) | 100 (87.2–100) | 18.52 (6.3–38.1) | Specificity, % (95% CI) | 47.62 (32.0–63.3) | 11.9 (4.0–25.6) | 100 (91.6–100) | +LR (95% CI) | 1.63 (1.2–2.3) | 1.14 (1.0–1.3) | — | −LR (95% CI) | 0.31 (0.1–0.8) | — | 0.81 (0.7–1.0) | +PV (95% CI) | 51.1 (42.9–59.2) | 42.2 (39.5–44.9) | 100 | −PV (95% CI) | 83.3 (65.7–92.9) | 100 | 65.6 (61.5–69.6) |
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MSC, morning serum cortisol; +LR, positive likelihood ratio; −LR, negative likelihood ratio; +PV, positive predictive value; −PV, negative predictive value.
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