The Bioinformatics Analysis of Aldosterone-Producing Adenoma and Verification of Differentially Expressed Genes

Table 2

The detailed information of downregulated DEG enrichment in the functional enrichment analysis of APAs.

ID	Analysis type	Process	Count	value	Genes
hsa05200	KEGG pathway	Pathways in cancer	9	3.49X10^−6	MMP2, PRKCA, GSTA2, EPAS1, PTGER3, FOS, JUN, GSTA5, HGF
hsa05205	KEGG pathway	Proteoglycans in cancer	6	7.90X10^−6	LUM, MMP2, DCN, PRKCA, GPC3, HGF
hsa05166	KEGG pathway	Human T-cell leukemia virus 1 infection	6	1.20X10^−5	HLA-DMA, ZFP36, FOS, JUN, ETS2, EGR1
GO: 0005515	Gene ontology	Protein binding	62	7.04X10^−15	ZNHIT2, USP2, NAALAD2…
GO: 0005615	Gene ontology	Extracellular space	23	5.70X10^−13	MMP2, SEMA3C, HBB…
GO: 0062023	Gene ontology	Collagen-containing extracellular matrix	13	3.59X10^−12	NID1, BGN, DCN…
GO: 0005576	Gene ontology	Extracellular region	21	6.49X10^−10	LUM, BGN, DCN…
GO: 0070062	Gene ontology	Extracellular exosome	21	5.66X10^−9	LUM, BGN, PRKCA…

DEG, differentially expressed gene; APA, aldosterone-producing adenoma.