Overexpression of PAX8-AS1 Inhibits Malignant Phenotypes of Papillary Thyroid Carcinoma Cells via miR-96-5p/PKN2 Axis

<div>Low expressed lncRNA PAX8-AS1 in PTC tissues and cells. <i>Note.</i> (a) ENCORI website (<a href="http://starbase.sysu.edu.cn/">http://starbase.sysu.edu.cn/</a>) showed the expression of PAX8-AS1 in THCA tissues (<i>n</i> = 510) and normal tissues (<i>n</i> = 58); (b) GEPIA website (<a href="http://gepia2.cancer-pku.cn/">http://gepia2.cancer-pku.cn/</a>) showed the expression levels of PAX8-AS1 in THCA tissues (<i>n</i> = 512) and normal tissues (<i>n</i> = 337); (c) GEPIA website showed the expression level of PAX8-AS1 in different stages of THCA patients; (d) the expression of PAX8-AS1 in PTC cell lines (K1, TPC-1, and IHH4) and human normal thyroid Nthy-ori 3-1 cells. <span class="nowrap"><svg height="11.6791pt" id="M2" style="vertical-align:-1.5766pt" version="1.1" viewbox="-0.0498162 -10.1025 209.807 11.6791" width="209.807pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 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International Journal of Endocrinology

fig1

Figure 1

Figure 1: Overexpression of PAX8-AS1 Inhibits Malignant Phenotypes of Papillary Thyroid Carcinoma Cells via miR-96-5p/PKN2 Axis 