| | Variables | Reference | Range | Overall | High OC | Low OC | p |
| | Number, n | — | — | 1635 | 819 | 816 | — | | Age (years), median (IQR) | — | 45–93 | 64.0 (14.0) | 63.0 (14.0) | 64.0 (15.0) | 0.684 | | YSM (years), median (IQR) | — | 1–45 | 14.0 (16.0) | 13.0 (16.0) | 14.0 (17.0) | 0.634 | | BMI (kg/m2), median (IQR) | — | 15.43–37.95 | 25.15 (4.94) | 24.75 (4.88) | 25.64 (4.89) | <0.001 | | Overweight or obese, n/N (%) | ≥24 kg/m2 | — | 1029/1635 (62.9%) | 465/819 (56.8%) | 564/815 (69.1%) | <0.001 | | Diabetes, n/N (%) | — | — | 406/1635 (24.8%) | 159/819 (19.4%) | 247/816 (30.3%) | <0.001 | | Diabetic duration (years), median (IQR) | — | 0.5–42.0 | 7.0 (8.1) | 6.0 (7.0) | 8.0 (9.0) | 0.062 | | FBG (mmol/L), median (IQR) | 3.9–6.1 | 1.90–18.40 | 5.46 (1.00) | 5.37 (0.90) | 5.57 (1.16) | <0.001 | | GA%, median (IQR) | 10.8–17.1 | 9.6–42.0 | 14.6 (2.3) | 14.5 (2.1) | 14.7 (2.4) | 0.104 | | TC (mmol/L), mean (SD) | 2.85–5.70 | 0.80–9.42 | 4.96 (1.05) | 5.11 (0.95) | 4.82 (1.12) | <0.001 | | Hypercholesterolemia, n/N (%) | >5.70 | — | 382/1635 (23.4%) | 218/819 (26.6%) | 164/816 (20.1%) | 0.002 | | TG (mmol/L), median (IQR) | 0.45–1.70 | 0.20–9.79 | 1.24 (0.88) | 1.21 (0.79) | 1.28 (0.96) | 0.022 | | Hypertriglyceridemia | >1.70 | — | 451/1635 (27.6%) | 200/819 (24.4%) | 251/816 (30.8%) | 0.004 | | HDL-C (mmol/L), median (IQR) | 0.93–1.81 | 0.14–2.48 | 1.26 (0.36) | 1.30 (0.34) | 1.22 (0.36) | <0.001 | | Low HDL-C, n/N (%) | <0.93 | — | 164/1635 (10.0%) | 40/819 (4.9%) | 124/816 (15.2%) | 0.001 | | LDL-C (mmol/L), mean (SD) | <3.37 | 0.38–6.06 | 2.91 (1.10) | 3.02 (0.79) | 2.83 (0.83) | <0.001 | | High LDL-C, n/N (%) | ≥3.37 | — | 467/1635 (28.6%) | 259/819 (31.6%) | 208/816 (25.5%) | 0.006 | | β-CTX (ng/ml), median (IQR) | 0.260–0.512 | 0.051–1.900 | 0.412 (0.260) | 0.539 (0.238) | 0.317 (0.151) | <0.001 | | P1NP (ng/ml), median (IQR) | 15.0–75.0 | 10.09–249.20 | 51.88 (25.56) | 62.90 (21.58) | 40.43 (16.66) | <0.001 | | OC (ng/ml), median (IQR) | 7.46–34.19 | 3.99–80.60 | 17.11 (8.05) | 21.59 (6.36) | 13.54 (4.06) | <0.001 | | PTH (pg/ml), median (IQR) | 12.0–68.0 | 6.73–200.20 | 36.44 (18.18) | 38.84 (17.76) | 33.99 (18.33) | <0.001 | | SHPT, n/N (%) | >68pg/ml | — | 82/1635 (5.0%) | 62/819 (7.6%) | 20/816 (2.5%) | <0.001 | | 25(OH)D (ng/ml), median (IQR) | 8.0–50.0 | 3.00–50.03 | 13.72 (9.25) | 13.70 (8.91) | 13.78 (9.42) | 0.742 | | Vitamin D insufficiency, n/N (%) | <20 ng/ml | — | 1295/1635 (79.2%) | 644/819 (78.6%) | 651/816 (79.8%) | 0.568 | | Vitamin D deficiency, n/N (%) | <30 ng/ml | — | 1583/1635 (96.8%) | 794/819 (96.9%) | 789/816 (96.7%) | 0.768 |
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n, number; SD, standard deviation; IQR, interquartile range; YSM, years since menopause; BMI, body mass index; FBG, fasting blood glucose; GA, glycated albumin; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ß-CTX, C-terminal telopeptide of type I collagen; P1NP, N-terminal prepeptide of type I procollagen; OC, osteocalcin; PTH, parathyroid hormone; SHPT, secondary hyperparathyroidism; 25(OH)D, 25-hydroxyvitamin D.
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