A Prediction Model for Contralateral Central Neck Lymph Node Metastases in Unilateral Papillary Thyroid Cancer

Table 3

Diagnostic value for suspicious lymph nodes in the contralateral central neck compartment of uni-PTC patients with or without Hashimoto’s thyroiditis on neck US.

Parameter	Without Hashimoto’s thyroiditis			Hashimoto’s thyroiditis
	Con-CLNM (+) (%)	Con-CLNM (−) (%)		Con-CLNM (+) (%)	Con-CLNM (−) (%)
Abnormal US	30 (71.4)	12 (28.6)	<0.001	14 (32.6)	29 (67.4)	0.033
Normal US	20 (22.7)	68 (77.3)		11 (14.3)	66 (85.7)
Value of neck US in diagnosis of suspicious lymph nodes
Sensitivity	60.0%			56.0%
Specificity	85.0%			69.5%
PPV	71.4%			32.6%
NPV	77.3%			85.7%
Accuracy	73.1%			66.7%

Note: Variables with statistical significance are shown in bold; the chi-square test was adopted. Abbreviations: con-CLNM, contralateral central lymph node metastasis; uni-PTC, unilateral papillary thyroid carcinoma; PPV, positive predictive value; NPV, negative predictive value; US, ultrasonography.