High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome

Table 1

Clinical and biochemical characteristics of controls and MetS subjects.

Variables	Controls	MetS	value
No. of subjects	162	131	—
Gender, M/F	78/84	65/66	0.802
Age (years)	49.47 ± 9.16	50.90 ± 9.45	0.236
Recent smoking (%)	18.5	26.7	0.093
BMI (kg/m^2)	23.28 ± 2.49	25.52 ± 3.02	<0.001
Waist circumference (cm)	81.3 ± 7.5	87.2 ± 8.9	<0.001
Fat (%)	27.61 ± 5.57	29.66 ± 3.68	<0.001
SBP (mm Hg)	123.7 ± 14.2	133.4 ± 13.3	<0.001
DBP (mm Hg)	74.9 ± 8.9	82.2 ± 9.4	<0.001
TC (mmol/l)	4.73 ± 0.98	4.89 ± 1.05	0.181
TG (mmol/l)^a	1.10 (0.82, 1.39)	1.92 (1.58, 2.49)	<0.001
LDL cholesterol (mmol/l)	2.42 ± 0.90	2.60 ± 1.04	0.115
HDL cholesterol (mmol/l)	1.57 ± 0.36	1.18 ± 0.41	<0.001
FPG (mmol/l)^a	5.10 (4.74, 5.41)	6.26 (5.26, 8.89)	<0.001
2h-PG (mmol/l)^a	5.82 (5.49, 6.23)	7.71 (6.14, 15.04)	<0.001
FIns (mU/l)^a	7.20 (6.06, 8.79)	8.93 (7.78, 10.62)	<0.001
HOMA-IR^a	1.60 (1.30, 2.06)	2.53 (1.84, 3.93)	<0.001
IL-6 (ng/l)	12.62 ± 5.20	17.02 ± 6.32	<0.001
MCP-1 (ng/l)	118.95 ± 39.49	146.94 ± 52.41	<0.001

Values were given as means ± SD or median with interquartile range. ^aLog-transformed; MetS, metabolic syndrome; BMI, body mass index; Fat, percentage of body fat; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride, LDL, low-density lipoprotein; HDL, high-density lipoprotein; FPG, fasting plasma glucose; 2h-PG, 2-hour plasma glucose; FIns, fasting insulin; HOMA-IR, homeostasis model assessment of insulin resistance; IL-6, interleukin-6; MCP-1, monocyte chemotactic protein-1.