High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome

Table 3

Association of serum asprosin with MetS and IR in fully adjusted models.

Model adjustment	MetS			IR
	β	OR per 1 SD increase (95% CI)	value	β	OR per 1 SD increase (95% CI)	value
Model 1	0.014	1.076 (1.047, 1.106)	<0.001	0.071	1.074 (1.046, 1.102)	<0.001
Model 2	0.066	1.068 (1.039, 1.745)	<0.001	0.067	1.069 (1.042, 1.097)	<0.001
Model 3	0.055	1.056 (1.022, 1.092)	0.001	0.069	1.071 (1.042, 1.101)	<0.001
Model 4	0.052	1.054 (1.019, 1.089)	0.002	0.067	1.070 (1.041, 1.100)	<0.001
Model 5	0.044	1.044 (1.009, 1.081)	0.014

Model 1, adjusted for age and gender; Model 2, further adjusted for BMI; Model 3, further adjusted for lipid profiles (TC, TG, LDL-C, and HDL-C); Model 4, further adjusted for inflammatory markers (IL-6 and MCP-1); Model 5, further adjusted for HOMA-IR. IR, insulin resistance; BMI, body mass index; TC, total cholesterol; TG, triglycerides, LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; IL-6, interleukin-6; MCP-1, monocyte chemotactic protein-1. HOMA-IR, homeostasis model assessment of insulin resistance.