Clinical Utility of Preoperative Vitamin D3 Injection for Preventing Transient Hypocalcemia after Total Thyroidectomy

Table 2

Comparison of perioperative biochemical characteristics between vitamin D3 injection (VDI) and vitamin D3 noninjection (VDN) groups.

	VDI (n = 342)	VDN (n = 1952)	value
Preop. 25-OHD (ng/mL)	16.5 ± 6.9 (range, 5.5–55.5)	19.4 ± 8.7 (range, 3.5–87.4)	<0.001
Preop. PTH (pg/mL)	45.9 ± 15.4 (range, 5.8–119.8)	44.7 ± 16.5 (range, 4.7–176.2)	0.197
Postop. PTH (pg/mL)	21.6 ± 14.4 (range, 1.8–90.9)	22.2 ± 16.0 (range, 1.2–126.7)	0.469
Preop. Ca (mg/dL)	9.6 ± 0.4 (range, 6.1–11.1)	9.6 ± 0.4 (range, 7.7–11.9)	0.578
Postop. Ca (mg.dL)	8.1 ± 0.6 (range, 6.4–9.7)	8.2 ± 0.6 (range, 6.0–10.7)	0.373
Preop. P (mg/dL)	3.7 ± 0.5 (range, 2.1–5.4)	3.6 ± 0.5 (range, 2.0–5.7)	0.272
Postop. P (mg/dL)	4.3 ± 0.8 (range, 2.1–7.3)	4.3 ± 0.7 (range, 2.0–7.9)	0.928
Preop. Ionized Ca (mg/dL)	4.8 ± 0.2 (range, 4.0–5.4)	4.8 ± 0.2 (range, 3.1–6.2)	0.286
Postop. Ionized Ca (mg/dL)	4.4 ± 0.2 (range, 3.6–5.2)	4.4 ± 0.3 (range, 3.3–5.8)	0.139

Data are expressed as mean ± SD. A statistically significant difference was defined as  < 0.05. preop., preoperative; postop., postoperative; 25-OHD, 25-hydroxyvitamin D; PTH, parathyroid hormone; Ca, calcium; P, phosphorus.