Clinical Utility of Preoperative Vitamin D3 Injection for Preventing Transient Hypocalcemia after Total Thyroidectomy

Table 4

Comparison of perioperative biochemical characteristics of patients with transient hypocalcemia between vitamin D3 injection (VDI) and vitamin D3 noninjection (VDN) groups.

	VDI (n = 67)	VDN (n = 571)	value
Preop. 25-OHD (ng/mL)	15.2 ± 6.0 (range, 6.3–41.5)	19.2 ± 8.4 (range, 4.2–56.4)	<0.001
Preop. PTH (pg/mL)	47.7 ± 2.2 (range, 22.5–94.1)	45.3 ± 17.5 (range, 19.2–166.2)	0.276
Postop. PTH (pg/mL)	8.1 ± 14.4 (range, 3.8–15.6)	8.0 ± 5.9 (range, 1.2–90.2)	0.982
Preop. Ca (mg/dL)	9.5 ± 0.3 (range, 8.7–10.4)	9.6 ± 0.4 (range, 7.7–10.7)	0.370
Postop. Ca (mg.dL)	7.7 ± 0.5 (range, 6.4–9.0)	7.8 ± 0.5 (range, 6.0–9.1)	0.868
Preop. P (mg/dL)	3.7 ± 0.5 (range, 2.6–4.9)	3.7 ± 0.5 (range, 2.3–5.7)	0.280
Postop. P (mg/dL)	4.8 ± 0.9 (range, 2.8–7.3)	4.7 ± 0.8 (range, 2.0–7.9)	0.156
Preop. Ionized Ca (mg/dL)	4.8 ± 0.2 (range, 4.4–5.1)	4.8 ± 0.2 (range, 4.3–5.6)	0.368
Postop. Ionized Ca (mg/dL)	4.2 ± 0.2 (range, 3.9–4.6)	4.2 ± 0.2 (range, 3.5–4.8)	0.637

Data are expressed as mean ± SD. A statistically significant difference was defined as  < 0.05. preop., preoperative; postop., postoperative; 25-OHD, 25-hydroxyvitamin D; PTH, parathyroid hormone; Ca, calcium; P, phosphorus.