TNRC6C Functions as a Tumor Suppressor and Is Frequently Downregulated in Papillary Thyroid Cancer

Table 4

The association between potential target genes and clinicopathological features of PTC.

Gene symbol	T classification	N classification	Clinical stage	Histological type
SCD	ns	<0.001	ns	ns
CRLF1	ns	<0.001	ns	0.015
APCDD1L	0.001	<0.001	0.006	<0.001
CTHRC1	0.008	<0.001	0.002	<0.001
PTPRU	0.035	<0.001	ns	0.005
ALDH1A3	ns	<0.001	ns	0.006
VCAN	<0.001	<0.001	<0.001	<0.001
TNC	<0.001	<0.001	0.011	<0.001
ECE1	ns	<0.001	ns	ns
COL1A1	<0.001	<0.001	<0.001	<0.001
CAMK2N2	ns	ns	ns	ns
MMP14	0.008	<0.001	0.047	0.002

Expression levels of genes were divided into two groups according to the median. The associations of expression levels of genes with clinicopathological features of PTC were analyzed using chi-square test. The significant results indicated that higher expression levels were associated with worse clinicopathological features of PTC.