Clinical Manifestations of Hyperandrogenism and Ovulatory Dysfunction Are Not Associated with His1058 C/T SNP (rs1799817) Polymorphism of Insulin Receptor Gene Tyrosine Kinase Domain in Kashmiri Women with PCOS

Table 3

Association of INSR C/T SNP (rs1799817) genotypes with body mass index in PCOS.

Clinical parameter		CC (n = 156)	CT (n = 74)	TT (n = 19)	(χ^2)
Body mass index	Obese	20 (12.82%)	8 (10.81%)	3 (15.78%)	(0.39) 0.82
	Overweight	51 (32.69%)	21 (28.37%)	8 (42.10%)	(1.36) 0.50
	Normal	67 (42.94%)	33 (44.59%)	6 (31.57%)	(1.07) 0.58
	Underweight	18 (11.53%)	12 (16.21%)	2 (10.52%)	(0.78) 0.67

Data presented as number (percent). Clinical features defined as follows: obese BMI ≥30 kg/m², overweight BMI ≥25–29.99 kg/m², normal BMI ≥18.6–24.99 kg/m², and underweight BMI ≤18.5 kg/m², (χ²). : value of CC vs. CT vs. TT calculated by Pearson chi-square test.