Clinical Manifestations of Hyperandrogenism and Ovulatory Dysfunction Are Not Associated with His1058 C/T SNP (rs1799817) Polymorphism of Insulin Receptor Gene Tyrosine Kinase Domain in Kashmiri Women with PCOS

Table 4

Comparison of the present study with previous studies of INSR gene exon 17 C/T (rs1799817) polymorphism and PCOS.

Author	Year	Ethnicity/country	Case/controls	value
Conway et al. [39]	1994	Caucasian/British	22/8	1.00
Siegel et al. [21]	2002	Caucasian/USA	99/136	0.32 obese/0.03 lean
Talbot et al. [40]	2006	Caucasian/British	24/5	0.25
Lee et al. [41]	2006	Asian/South Korean	132/100	0.35
Unsal et al. [19]	2009	Caucasian/Turkish	44/50	0.53
Mukherjee et al. [15]	2009	South Asian/Indian	180/144	0.05
Ranjzad et al. [42]	2012	Asian/Iranian	181/181	0.42
Kashima et al. [28]	2013	Asian/Japanese	61/99	0.17
Tehrani et al. [27]	2013	Caucasian/Iranian	186/156	0.62
Skrgatić et al. [13]	2013	Caucasian/Croatia	150/170	0.86
Mutib et al. [43]	2014	Caucasian/Iraqi	84/65	<0.001
Bagheri et al. [44]	2015	Asian/Iranian	50/47	0.52
Feng et al. [20]	2015	Meta-analysis	1158/1264	0.48
Gangopadhyay et al. [26]	2016	South Asian/Indian	50/50	0.008
Shi et al. [32]	2016	Meta-analysis	1145/1065	0.66
Thangavelu et al. [22]	2017	South Asian/Indian	169/169	0.80
Present study	2021	South Asian/Kashmiri	249/100	0.15