Discovery of a Novel Variant of SEMA3A in a Chinese Patient with Isolated Hypogonadotropic Hypogonadism

Figure 3

Schematic representation of the SEMA3A protein. Location of the SEMA3A variants characterized in IHH. Four variants caused impaired secretion of SEMA3A highlighted in yellow. SEMA, semaphorin domain; PSI, plexin/semaphorin/integrin domain; Ig, immunoglobulin-like domain; C, cysteine residue.