PERK-Dependent Activation of the JAK2/STAT3 Pathway Contributes to High Glucose-Induced Extracellular Matrix Deposition in Renal Tubular Epithelial Cells

Table 2

The protein levels of TGF-β₁, FN, and collagen I in different concentrations of thapsigargin at different times.

	TGF-β1 (ng/L)		FN (μg/ml)		Coll I (ng/L)
	Mean ± SD		Mean ± SD		Mean ± SD
NC	1214.17 ± 107.99	—	595.82 ± 96.72	—	87.53 ± 9.22	—
DMSO	1207.90 ± 77.80	1.00	607.90 ± 88.25	1.00	89.16 ± 12.42	1.00
Thap, 0.1/6 h	1324.93 ± 117.29	0.98	689.67 ± 98.39	0.95	117.98 ± 26.66	0.73
Thap, 0.1/24 h	1868.72 ± 121.23	<0.05	983.82 ± 100.21	<0.05	190.99 ± 25.37	<0.05
Thap, 0.1/48 h	1546.91 ± 150.47	0.20	755.08 ± 109.47	0.59	135.02 ± 24.07	0.51
Thap, 0.2/6 h	1318.07 ± 181.84	0.99	772.14 ± 113.70	0.47	138.21 ± 23.80	0.19
Thap, 0.2/24 h	1794.28 ± 157.11	<0.05	896.43 ± 105.48	0.04	157.87 ± 20.64	0.03
Thap, 0.2/48 h	1423.61 ± 242.25	0.70	744.88 ± 119.11	0.66	115.34 ± 26.64	0.80

N = 3, compared with the NC group.