Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive Bioinformatics Analysis

Figure 8

Hub genes’ expression was related to macrophage’s proinflammation in adipose tissue. (a) Immunofluorescence staining for CD68 and CSF1R in the VAT tissue from IRO patients. Scale bar = 40 um. (b) Immunofluorescence staining for CD68 and C1QC in the VAT tissue from IRO patients. Scale bar = 40um. (c) Immunohistochemical staining for CSF1R and C1QC in the VAT tissue between IRO patients group and IS group. The scale bar is 100 um and 40 um, respectively. (d) Immunohistochemical staining for CD68 and CSF1R in the VAT tissue between ND-fed mice group and HFD-fed mice group. (e) Quantitative analysis of IHC results of hub genes. value <0.05. value <0.01. value <0.001.

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