Thyroid Nodules Located in the Lower Pole Have a Higher Risk of Malignancy than Located in the Isthmus: A Single-Center Experience
Table 4
Comparison of postoperative pathological outcomes with demographic and clinical characteristics.
Variables
Postoperative pathological outcomes
Benign (n = 998)
Malignant (n = 102)
Incidental (n = 42)
Age
52.57 ± 12.92a
48.93 ± 12.50b
53.62 ± 11.19ab
0.019
Gender
Female
798 (80.0)
82 (80.4)
30 (71.4)
0.391
Male
199 (20.0)
20 (19.6)
12 (28.6)
TSH (mIU/L)
1.33 (0.74–2.40)a
1.88 (0.97–2.70)b
0.97 (0.31–1.79)c
0.001
Nodule size (mm)
17.6 (13.0–25.0)a
16.0 (12.0–27.5)a
24.1 (18.0–33.5)b
0.013
<10
69 (6.9)a
11 (10.8)a
4 (9.5)a
0.022
10–20
519 (52.1)a
49 (48.0)a
11 (26.2)b
20–40
340 (34.1)a
34 (33.3)a
21 (50.0)a
>40
68 (6.8)a
8 (7.8)a
6 (14.3)a
MTN
No
338 (34.0)a
37 (36.6)a
5 (11.9)b
0.009
Yes
657 (66.0)a
64 (63.4)a
37 (88.1)b
Nodule number
2.00 (1.00–4.00)a
2.00 (1.00–3.00)a
3.00 (2.00–5.25)b
0.020
Hashimoto’s
No
895 (89.9)
91 (90.1)
31 (83.8)
0.471
Yes
100 (10.1)
10 (9.9)
6 (16.2)
Hyperthyroidism
No
941 (94.6)ab
100 (99.0)a
31 (86.1)b
0.009
TMNG
37 (3.7)a
1 (1.0)a
1 (2.8)a
Grave’s
8 (0.8)a
0 (0.0)a
0 (0.0)a
Iatrogenic
9 (0.9)a
0 (0.0)a
4 (11.1)b
Data are expressed in mean ± standard deviation n (%) and median (1st quartile-3 rd. quartile). Similar letters on the same line indicate similarity between groups and different letters indicate differences between groups.