Thyroid Nodules Located in the Lower Pole Have a Higher Risk of Malignancy than Located in the Isthmus: A Single-Center Experience

Table 7

Evaluation of risk factors affecting malignancy status for FNAB results.

Variables	Univariate		Multivariate
	OR (%95 CI)		OR (%95 CI)
Age	0.99 (0.95–1.01)	0.44
Gender
Female	1	—
Male	1.07 (0.39–2.92)	0.89
TSH	1.14 (0.89–1.45)	0.28
Hashimoto’s	1.32 (0.38–4.55)	0.65
MTN
No	1	—
Yes	0.34 (0.15–0.77)	0.011
Nodule size	0.96 (0.92–1.01)	0.174
Nodule number	0.70 (0.51–0.95)	0.024	0.70 (0.50–0.97)	0.034
Doppler US
No blood flow	1	—	1	—
Peripheral blood flow	0.10 (0.02–0.44)	0.002	0.09 (0.02–0.40)	0.001
Central blood flow	2.36 (0.76–7.30)	0.134	2.16 (0.64–7.25)	0.211
Central and peripheral blood flow	0.44 (0.14–1.44)	0.179	0.38 (0.11–1.26)	0.115
Sum of right and left lobes
Isthmus	1	—
Lower	3.38 (0.39–29.44)	0.26
Middle	4.76 (0.60–37.72)	0.13
Upper	5.77 (0.68–48.78)	0.10
Whole lobe	2.14 (0.19–24.09)	0.53

CI: confidence interval; OR: odds ratio.