Research Article

Associations of TG/HDL Ratio with the Risk of Prediabetes and Diabetes in Chinese Adults: A Chinese Population Cohort Study Based on Open Data

Table 1

Baseline characteristics of the study participants.

VariablesTotal (n = 116,855)Impaired glucose toleranceDiabetes mellitus
Nonimpaired glucose tolerance (n = 107,028)Impaired glucose tolerance (n = 9773)
value
Nondiabetes (n = 114,682)Diabetes (n = 2173)
value

Age (year), mean ± SD44.1 ± 12.943.2 ± 12.554.2 ± 13.0<0.00143.9± 12.855.7 ± 12.6<0.001
Gender, n (%)
Male62,868 (53.8)56,332 (52.6)6536 (66.9)<0.00161,289 (53.4)1579 (72.7)<0.001
Female53,987 (46.2)50,750 (47.4)3237 (33.1)53,393 (46.6)594 (27.3)

Height (cm), mean ± SD166.3 ± 8.3166.3 ± 8.3166.5 ± 8.50.124166.3 ± 8.3166.9 ± 8.5<0.001
Weight (kg), mean ± SD64.9 ± 12.164.3 ± 11.970.8 ± 12.5<0.00164.7 ± 12.073.5 ± 13.0<0.001
BMI (kg/m2), mean ± SD23.3 ± 3.323.2 ± 3.225.4 ± 3.3<0.00123.3 ± 3.326.3 ± 3.4<0.001
FPG (mmol/L), mean ± SD4.9 ± 0.64.9 ± 0.65.7 ± 0.7<0.0014.9 ± 0.66.0 ± 0.7<0.001
HBP, n (%)
No99312 (85.0)92921 (86.8)6391 (65.4)<0.00197999 (85.5)1325 (61)<0.001
Yes17525 (15.0)14146 (13.2)3379 (34.6)16683 (14.5)848 (39)

Smoking, n (%)
Current smoker6672 (20.4)5878 (19.5)794 (30.6)<0.00119,349 (16.9)753 (34.7)<0.001
Ever smoker1328 (4.1)1190 (4)138 (5.3)3912 (3.4)123 (5.7)
Never smoker24,686 (75.5)23,022 (76.5)1664 (64.1)91,421 (79.7)1297 (59.7)

Drinking, n (%)
Current drinker878 (2.7)766 (2.5)112 (4.3)0.0132374 (2.1)89 (4.1)<0.001
Ever drinker5535 (16.9)5069 (16.8)466 (18)16,371 (14.3)411 (18.9)
Never drinker26,273 (80.4)24,255 (80.6)2018 (77.7)95,937 (83.7)1673 (77)

Cholesterol (mmol/L), median (IQR)4.7 (4.2, 5.3)4.7 (4.1, 5.3)5.0 (4.4, 5.6)<0.0014.7 (4.2, 5.3)5.0 (4.4, 5.7)<0.001
Triglyceride (mmol/L), median (IQR)1.1 (0.8, 1.7)1.1 (0.7, 1.6)1.6 (1.1, 2.3)<0.0011.1 (0.8, 1.6)1.8 (1.2, 2.6)<0.001
HDL (mmol/L), median (IQR)1.4 (1.2, 1.6)1.4 (1.2, 1.6)1.3 (1.1, 1.5)<0.0011.4 (1.2, 1.6)1.3 (1.1, 1.5)<0.001
LDL (mmol/L), median (IQR)2.7 (2.3, 3.2)2.7 (2.3, 3.1)2.8 (2.4, 3.3)<0.0012.7 (2.3, 3.2)2.8 (2.4, 3.3)<0.001
ALT (U/L), median (IQR)18.0 (13.0, 27.5)18.0 (12.9, 27.0)23.0 (16.2, 35.0)<0.00118.0 (13.0, 27.1)26.0 (18.1, 41.0)<0.001
AST (U/L), median (IQR)22.0 (18.7, 26.9)22.0 (18.4, 26.2)24.0 (20.0, 29.2)<0.00122.0 (18.7, 26.8)25.0 (21.0, 32.0)<0.001
CCR (umol/L), median (IQR)69.6 (58.0, 81.2)69.1 (57.7, 81.0)73.0 (62.0, 83.5)<0.00169.3 (57.9, 81.0)73.4 (63.0, 82.9)<0.001
TG/HDL, median (IQR)0.8 (0.5, 1.3)0.8 (0.5, 1.3)1.2 (0.8, 1.9)<0.0010.8 (0.5, 1.3)1.4 (0.9, 2.2)<0.001
BUN (mmol/L), median (IQR)4.6 (3.8, 5.4)4.5 (3.8, 5.3)4.9 (4.1, 5.7)<0.0014.6 (3.8, 5.4)4.9 (4.1, 5.8)<0.001

BMI: body mass index; FPG: fasting blood glucose; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ALT: alanine aminotransferase; AST: aspartate transaminase; CCR: creatinine clearance rate; BUN: blood urea nitrogen.