Impact of Novel Guidelines on Multifactorial Control and Its Association with Mortality in Adult Patients with Hypertension and Newly Diagnosed Type 2 Diabetes: A 4-Year Prospective Multicenter Study

Table 3

Univariate Cox analysis of factors associated with all-cause mortality in patients with hypertension and newly diagnosed diabetes after 4 years.

Variables	HR	95% CI
Age>75	4.3	1.7–11.0	0.002^∗
Gender (male)	1.2	0.5–3.0	0.768
Smoking	0.43	0.1–1.9	0.256
BMI	0.68	0.2–2.1	0.488
Very high risk	0.77	0.3–2	0.585
CKD	7.4	2.2–26.0	0.001^∗
CAD	0.97	0.38–2.5	0.994
Dyslipidemia	1.9	0.69–5.4	0.211
HF	3.1	0.71–13	0.135
AF	1.8	0.4–7.6	0.453
Stroke	1.2	0.16–9	0.865
≥2 comorbid conditions	3.0	1.2–7.9	0.022^∗
ACEi/ARB	0.36	0.1–1.1	0.068
Statin	1.7	0.6–5.2	0.345
Metformin	0.38	0.15–0.97	0.042^∗
≥2 risk factors controlled at baseline	0.79	0.3–2.1	0.63

^∗Statistically significant. BMI: body mass index; CAD: coronary artery disease; CKD: chronic kidney disease; AF: atrial fibrillation; HF: heart failure; COPD: chronic obstructive pulmonary disease; ACEi: angiotensin converting enzyme inhibitor, ARB: angiotensin receptor blocker.