Research Article
Metabolomics Identifies Biomarker Signatures to Differentiate Pancreatic Cancer from Type 2 Diabetes Mellitus in Early Diagnosis
Table 1
Demographic data of subjects.
| | Characteristic | PC group (n = 26) | DM group (n = 27) | Normal group (n = 23) |
| | Sex | | | | | Male | 14 | 14 | 12 | | Female | 12 | 13 | 11 | | Age (years, mean ± SD) | 64.74 ± 7.93∗ | 56.93 ± 9.93 | 60.22 ± 6.65 | | Underlying diseases | | | | | Acute coronary disease | 2# | 1 | 0 | | Hypertension | 1 | 1 | 1 | | Cerebral infarction | 1 | 1 | 0 | | Location | | | | | Head of pancreas | 15 | | | | Body of pancreas | 8 | | | | Tail of pancreas | 4 | | | | BMI (mean ± SD) | 19.32 ± 4.11#∗ | 22.98 ± 3.79 | 23.13 ± 3.62 | | Duration of DM (Mon, mean ± SD) | 10.97 ± 7.66∗ | 14.26 ± 8.54 | | | Fasting plasma glucose (GLU, mmoL/L, mean ± SD) | 7.32 ± 1.09# | 7.65 ± 1.43# | 5.11 ± 0.63 | | Glycosylated hemoglobin (HbAlc,%, median, range) | 8.9 (6.3, 11.5)# | 8.2 (5.8, 10.2)# | 4.7 (2.7, 6.4) | | CA19-9 (μ/ml, median, range) | 198.6 (31–530)#∗ | 4.2 (2.7, 10.2)# | 2.1 (1.3, 6.9) |
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Notes: #compared with the normal, ; ∗ compared with the DM, . |
