Serum Tenascin-C and Alarin Levels Are Associated with Cardiovascular Diseases in Type 2 Diabetes Mellitus

Table 4

Multivariable logistic regression models for severity of CVD.

Models		OR	95% CI
Tenascin-C
Crude	0.006	1.023	1.004–1.040
Model 1	0.046	1.019	1.000–1.038
Model 2	0.018	1.028	1.005–1.052
Model 3	0.019	1.038	1.006–1.071
Alarin
Crude	0.019	1.023	1.006–1.040
Model 1	0.007	1.032	1.000–1.056
Model 2	0.003	1.046	1.015–1.077
Model 3	0.003	1.053	1.018–1.089

Model 1, adjusted for age, sex, BMI and WHR; Model 2, adjusted for Model 1+ duration of diabetes, HbAlc, HOMA-IR, DN and DR; Model 3, adjusted for Model 2+ TG, TC, LDL-C, HDL-C, hypertension and smoking status. BMI, body mass index; CI, confidence interval; CVD, cardiovascular diseases; DN, diabetic nephropathy; DR, diabetic retinopathy; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance index; LDL-C, low-density lipoprotein cholesterol; OR, odds ratio; TC, total cholesterol; TG, triglycerides; WHR, waist-hip ratio.