Bidirectional Mendelian Randomization Analysis for Vitamin D and Thyroid Peroxidase Antibody

Table 6

Associations of TPOAb_GRS and TPOAb concentration with 25 (OH) D.

	Model 1	Model 2
TPOAb_GRS	−0.031 (−0.090, 0.029)	−0.030 (−0.091, 0.030)
Tertiles of TPOAb_GRS
Q1	0.000 (ref.)	0.000 (ref.)
Q2	0.003 (−0.012, 0.018)	0.003 (−0.012, 0.018)
Q3	−0.005 (−0.021, 0.011)	−0.005 (−0.021, 0.011)
For trend	0.571	0.586
TPOAb	0.006 (0.000, 0.011)	0.006 (0.000, 0.011)

Data were presented as and 95% confidence interval. 25 (OH) D, 25-hydroxyvitamin D; GRS, genetic risk score; Model 1 adjusted for age and sex; Model 2 adjusted for terms in model 1 and waist to hip ratio.