Research Article
Male Gender Is Associated with Lymph Node Metastasis but Not with Recurrence in Papillary Thyroid Carcinoma
Table 1
Demographic and clinicopathologic characteristics of male and female papillary thyroid carcinoma patients.
| | Characteristics | Total (N = 2536), no. (%) | Male (N = 639) | Female (N = 1897) | value |
| | Age (y) | 42.9 ± 11.9 | 42.7 ± 11.4 | 42.9 ± 12.2 | 0.586 | | <35 | 712 (28.1) | 176 (27.5) | 536 (28.3) | 0.607 | | 35–55 | 1417 (55.9) | 367 (57.5) | 1050 (55.3) | | | ≥55 | 407 (16.0) | 96 (15.0) | 311 (16.4) | | | Tumor size (mm) | 12.1 ± 8.3 | 11.9 ± 7.9 | 12.2 ± 8.4 | 0.612 | | ≤10 | 1429 (56.3) | 353 (55.2) | 1076 (56.7) | 0.397 | | 10–20 | 830 (32.7) | 222 (34.7) | 608 (32.1) | | | >20 | 277 (11.0) | 64 (10.1) | 213 (11.2) | | | Bilateral | | | | 0.614 | | Yes | 393 (13.7) | 103 (16.1) | 290 (15.3) | | | No | 2143 (86.3) | 536 (83.9) | 1607 (84.7) | | | Tumor location | | | | 0.911 | | Superior pole | 541 (21.3) | 135 (21.1) | 406 (21.4) | | | Others | 1995 (78.7) | 504 (78.9) | 1491 (78.6) | | | Multifocality | | | | 0.812 | | Presence | 453 (17.9) | 116 (18.2) | 337 (17.8) | | | Absence | 2083 (82.1) | 523 (81.8) | 1560 (82.2) | | | Extrathyroid extension | | | | 0.630 | | Presence | 865 (34.1) | 223 (34.9) | 642 (33.8) | | | Absence | 1671 (65.9) | 416 (65.1) | 1255 (66.2) | | | CLT | | | | <0.001 | | Yes | 526 (20.7) | 68 (10.6) | 458 (24.1) | | | No | 2010 (79.3) | 571 (89.4) | 1439 (75.9) | | | LNM | | | | <0.001 | | Yes | 1391 (54.9) | 420 (65.7) | 971 (51.2) | | | No | 1145 (45.1) | 219 (34.3) | 926 (48.8) | | | CLNM | | | | <0.001 | | Yes | 1341 (52.5) | 410 (64.2) | 921 (48.6) | | | No | 1205 (47.5) | 229 (35.8) | 976 (51.4) | | | LLNM | | | | 0.003 | | Yes | 558 (22.0) | 168 (26.3) | 390 (20.6) | | | No | 1978 (78.0) | 471 (73.7) | 1507 (79.4) | | | Recurrence | 29 (1.1) | 11 (1.7) | 18 (0.9) | 0.131 |
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Continuous data are shown as mean ± standard deviation. CLT, chronic lymphocytic thyroiditis; LNM, lymph node metastasis.
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