Male Gender Is Associated with Lymph Node Metastasis but Not with Recurrence in Papillary Thyroid Carcinoma

Table 2

Univariate and multivariate logistic regression analyses of factors associated with lymph node metastasis.

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)		OR (95% CI)
Gender (male/female)	1.83 (1.52–2.20)	<0.001	1.93 (1.59–2.35)	<0.001
Age (y)		<0.001		<0.001
<35	Reference		Reference
35–55	0.56 (0.47–0.68)	<0.001	0.58 (0.48–0.70)	<0.001
≥55	0.46 (0.36–0.59)	<0.001	0.42 (0.33–0.55)	<0.001
Tumor size (mm)		<0.001		<0.001
≤10	Reference		Reference
10–20	2.24 (1.88–2.67)	<0.001	2.09 (1.75–2.52)	<0.001
>20	4.47 (3.30–6.06)	<0.001	4.18 (3.06–5.73)	<0.001
ETE (+/−)	1.49 (1.27–1.77)	<0.001	1.31 (1.10–1.57)	0.003
Multifocality (+/−)	2.01 (1.62–2.49)	<0.001	1.92 (1.53–2.41)	<0.001
Tumor location
Superior pole	Reference	0.980
Others	0.99 (0.82–1.21)
Bilateral (+/−)	2.24 (1.77–2.83)	<0.001
CLT (+/−)	0.91 (0.75–1.11)	0.349

CLT, chronic lymphocytic thyroiditis; ETE, extrathyroid extension; −, negative; +, positive.