Central Obesity Is Associated with Variations in TSH and ACTH Levels among Euthyroid Obese Individuals

Table 3

The distribution of demographic data and metabolic indicators across the TSH quartiles in the male subgroup.

TSH quartiles (μIU/ml)		≤1.55	1.56–2.24	2.25–3.14	≥3.15	value
Age (year)	N	36	40	23	23	0.219
	Mean ± SD	32.2 ± 10.5	34.3 ± 13.3	28.7 ± 10.3	29.7 ± 9.1
FT3 (pmol/L)	N	12	18	8	11	0.207
	Mean ± SD	5.20 ± 0.75	4.76 ± 0.81	4.81 ± 0.87	5.32 ± 0.71
FT4 (pmol/L)	N	12	17	7	11	0.063
	Mean ± SD	16.66 ± 2.73	14.77 ± 1.77	16.04 ± 1.67	17.08 ± 3.03
TT3 (nmol/L)	N	35	37	23	23	0.365
	Mean ± SD	1.74 ± 0.29	1.77 ± 0.32	1.84 ± 0.34	1.86 ± 0.28
TT4 (nmol/L)	N	35	37	23	23	0.390
	Mean ± SD	99.4 ± 20.7	96.5 ± 19.5	104.2 ± 21.3	104.6 ± 23.2
Weight (kg)	N	36	40	24	23	0.594
	Mean ± SD	103.7 ± 26.8	104.6 ± 19.1	109.8 ± 19.3	117.8 ± 17.2
BMI (kg/m^2)	N	36	40	24	23	0.017
	Mean ± SD	34.4 ± 5.1	34.6 ± 5.2	35.3 ± 4.7	38.3 ± 3.9
WC (cm)	N	35	40	24	23	0.185
	Mean ± SD	111.7 ± 10.5	110.8 ± 14.6	113.3 ± 12.0	117.5 ± 9.1
HC (cm)	N	35	40	24	23	0.036
	Mean ± SD	114.3 ± 9.2	114.1 ± 12.1	115.8 ± 10.2	121.8 ± 10.4
BF (%)	N	35	40	24	23	0.566
	Mean ± SD	39.8 ± 3.25	36.5 ± 5.1	38.3 ± 5.5	39.8 ± 5.9
Muscle mass of upper extremities (kg)	N	27	36	20	21	0.075
	Mean ± SD	7.76 ± 1.45	7.41 ± 1.04	7.74 ± 1.07	8.32 ± 1.40
Muscle mass of lower extremities (kg)	N	27	36	20	21	0.053
	Mean ± SD	20.82 ± 3.71	19.67 ± 2.33	21.06 ± 2.72	21.88 ± 3.22
Muscle mass (kg)	N	27	36	20	21	0.093
	Mean ± SD	37.65 ± 6.52	36.08 ± 4.33	37.39 ± 4.58	39.89 ± 6.24
BMR (kCal)	N	33	39	23	22	0.331
	Mean ± SD	1850.7 ± 274.6	1806.6 ± 277.8	1885.5 ± 257.6	1935.9 ± 271.4
Fasting insulin (μIU/ml)	N	26	29	21	17	0.194
	Mean ± SD	22.78 ± 2.48	28.12 ± 3.66	27.91 ± 4.46	35.18 ± 4.74
Fasting C-peptide (ng/ml)	N	26	27	21	16	0.471
	Mean ± SD	4.10 ± 1.39	3.81 ± 1.33	4.57 ± 2.49	4.34 ± 1.42
Cortisol (μg/dl)	N	28	29	22	16	0.448
	Mean ± SD	15.74 ± 6.79	15.85 ± 8.06	13.09 ± 5.62	15.68 ± 5.39
ACTH (pg/ml)	N	28	28	21	17	0.003
	Mean ± SD	32.61 ± 21.84	32.36 ± 14.44	27.54 ± 16.05	50.10 ± 23.67
HbA1c (%)	N	20	24	14	13	0.648
	Mean ± SD	7.01 ± 1.65	7.05 ± 2.30	6.29 ± 1.04	6.88 ± 2.02
UA (μmol/L)	N	29	31	20	18	0.862
	Mean ± SD	459.9 ± 23.2	435.2 ± 20.0	451.5 ± 33.6	431.1 ± 38.2
Testosterone (ng/ml)	N	8	19	13	7	0.474
	Mean ± SD	3.84 ± 1.22	3.60 ± 1.76	2.96 ± 1.21	3.16 ± 0.75

BMR, basal metabolic rate; BMI, body mass index; WC, waist circumference; HC, hip circumference; BF, body fat percentage; ACTH, adrenocorticotropic hormone; UA, uric acid.