The Association between Baseline, Changes in Uric Acid, and Renal Failure in the Elderly Chinese Individuals: A Prospective Study with a 3-Year Follow-Up
Table 2
Logistic regression analysis of baseline SUA levels and the development of CKD.
SUA quartiles
Odds ratio (95% confidence interval)
Unadjusted
Model 1
Model 2
Model 3
Q1 (<4.8 md/dl)
1.00 (reference)
1.00 (reference)
1.00 (reference)
1.00 (reference)
Q2 (<5.7 mg/d)
1.72 (1.00–2.96)
1.93 (1.09–3.40)
1.82 (1.02–3.25)
1.79 (1.00–3.22)
Q3 (<6.5 mg/dl)
3.29 (1.85–5.84)
3.96 (2.13–7.35)
3.53 (1.87–6.67)
3.40 (1.79–6.47)
Q4 (≥6.5 mg/dl)
5.4 (2.92–9.98)
6.76 (3.44–13.25)
6.43 (3.21–12.87)
6.79 (3.45–13.75)
P for linear trend
<0.001
<0.001
<0.001
<0.001
SUA (per 1 mg/dl increase)
1.66 (1.40–1.96)
1.78 (1.47–2.15)
1.74 (1.43–2.11)
1.76 (1.45–2.14)
Normal SUA
1.00 (reference)
1.00 (reference)
1.00 (reference)
1.00 (reference)
Hyperuricemia
3.68 (2.11–6.40)
3.58 (2.03–6.31)
3.41 (1.91–6.09)
3.68 (2.03–6.66)
Model 1 was adjusted for age, sex, and BMI. Model 2 was adjusted for Model 1, TGs, TC, HDL. Model 3 was adjusted for Model 2, diabetes, hypertension, chronic cardiovascular disease, ACEI/ARB usage.
