The Predictive Levels of Serum Anti-Müllerian Hormone and the Combined Index of the Number of Retrieved Oocytes and Good-Quality Embryos in Advanced-Age Infertile Women
Table 3
The ROC curve, AUC, and cutoff values of variables on predicting oocyte retrieval.
Subjects
Variables
AUC
Cutoff value
Sensitivity (%)
Specificity (%)
Value (95% confidence interval)
value
All subjects
AMH
0.802 (0.738, 0.857)
<0.0011
>1.4
78.46
82.76
AMH/age ratio
0.760 (0.692, 0.819)
<0.0011
0.0279
85.77
72.41
Maternal age
0.773 (0.706, 0.831)
0.0115
>38
41.87
82.76
FSH/LH ratio
0.670 (0.597, 0.737)
0.0460
≤1.331
32.63
100.00
ORPI
0.684 (0.612, 0.750)
0.0011
>0.261
82.03
63.16
TT
0.728 (0.658, 0.790)
0.0323
>0.16
91.20
55.56
21–34 years#
AFC/age ratio
0.691 (0.539, 0.818)
0.0171
>0.741
47.50
100.00
AMH
0.779 (0.634, 0.887)
<0.0011
>3.06
56.36
100.00
AMH/age ratio
0.796 (0.654 0.900)
<0.0011
>0.096
58.18
100.00
ORPI
0.768 (0.622, 0.878)
0.0012
>1.927
55.00
100.00
35–46 years†
AMH
0.982 (0.948, 0.996)
<0.0011
>1.37
77.35
100.00
AMH/age ratio
0.988 (0.957, 0.998)
<0.0011
>0.028
84.44
95.00
ORPI
0.988 (0.957, 0.998)
<0.0011
>0.261
80.23
100.00
TT
0.920 (0.868, 0.956)
<0.0011
0.16
90.10
100.00
AFC, antral follicle count; AMH, anti-Müllerian hormone; AUC, the area under the curve; FSH, follicle-stimulating hormone; LH, luteinizing hormone; ORPI, ovarian response prediction index; ROC curve, receiver operating characteristic curve; TT, total testosterone. Pairwise comparison of ROC curves: AMH vs. AMH/age ratio: ; AMH vs. ORPI: ; AMH/age ratio vs. ORPI: .#Pairwise comparison of ROC curves: all P>0.05. †Pairwise comparison of ROC curves: AMH vs. TT: ; AMH/age ratio vs. TT: ; ORPI vs. TT: .