Research Article
Changes in Physiological Levels of Cortisol and Adrenocorticotropic Hormone upon Hospitalization Can Predict SARS-CoV-2 Mortality: A Cohort Study
Table 1
Baseline characteristic of patients with COVID-19.
| | Variables | No. (%) | Median (interquartile range (IQR)) |
| | Gender | | | | Male | 81 (52.6) | | | Female | 73 (47.4) | | | Age category | | | | ≤50 yrs | 68 (44.2) | | | >50 yrs | 86 (55.8) | | | Oxygen therapy | | | | No | 18 (11.7) | | | Yes | 136 (88.3) | | | Mechanical ventilator | | | | No | 142 (92.8) | | | Yes | 11 (7.2) | | | ICU administration | | | | No | 120 (77.9) | | | Yes | 33 (21.4) | | | C-reactive protein (qualitative; normal range 0) | | | | Negative | 34 (22.5) | | | 1+ | 23 (15.2) | | | 2+ | 33 (21.9) | | | 3+ | 48 (31.8) | | | 4+ | 13 (8.6) | | | Have underlying disease | | | | No | 85 (55.6) | | | Yes | 68 (44.4) | | | Age (years) | | 53 (40.0–65.3) | | Serum cortisol level (μg/dl) | | 15.6 (11.6–21.2) | | Plasma ACTH level (pg/ml) | | 11.4 (5.8–18.0) | | Systolic blood pressure (mmHg) | | 118.5 (110.0–130.0) | | Diastolic blood pressure (mmHg) | | 75 (70.0–80.0) | | Body temperature (°C) | | 37 (36.8–37.5) | | SPO2 (%) | | 91.0 (88.0–95.0) | | Hospitalized day | | 4.0 (3.0–6.0) | | Sodium (mEq/L) | | 138 (136.0–141.0) | | Potassium (mEq/L) | | 4.1 (3.8–4.3) | | D-dimer (ng/ml) | | 200 (100.0–409.8) | | Creatinine (mg/dl) | | 1.0 (0.9–1.2) | | Glucose (mg/dl) | | 116.0 (98.0–149.0) | | WBC (per mm3) | | 6100.0 (4800.0–7550.0) | | Neutrophil (%) | | 75.0 (65.6–82.9) | | Lymphocyte (%) | | 21.5 (15.0–29.6) | | Erythrocyte sedimentation rate (mm/h) | | 30.0 (13.0–50.0) | | Neutrophil-lymphocyte ratio (NLR) | | 3.3 (2.3–5.7) |
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