Changes in Physiological Levels of Cortisol and Adrenocorticotropic Hormone upon Hospitalization Can Predict SARS-CoV-2 Mortality: A Cohort Study

Table 3

Multivariate logistic regression analysis on factors related to death among patients with COVID-19.

Variable	Coefficient	Wald statistics	Adjusted odds ratio (95% CI)	value
Age	0.099	1.925	1.10 (0.96–1.27)	0.165
Serum cortisol level (μg/dl)	−0.298	3.922	0.74 (0.55–0.99)	0.048
D-dimer (ng/ml)	0.002	6.353	1.002 (1.001–1.004)	0.012
Serum creatinine (mg/dl)	0.174	0.129	1.190 (0.46–3.08)	0.719
Body temperature (°C)	0.817	0.278	2.265 (0.11–47.16)	0.598
SPO2 (%)	−0.099	0.436	0.91 (0.67–1.22)	0.509
ICU administration	−0.415	0.071	0.66 (0.03–13.98)	0.790
Having underlying disease	5.560	3.860	259.80 (1.01–66604.06)	0.049
Mechanical ventilator	4.527	5.355	92.45 (2.00–4274.47)	0.021
NLR	0.122	0.360	1.13 (0.76–1.68)	0.549

CI = confidence interval; SPO2 = pulse oximetry O2 saturation; NLR = neutrophil-lymphocyte ratio; ICU: intensive care unit; significant at level 0.05.