Contrast-Enhanced Ultrasound: An Effective Method for Noninvasive Diagnosis of Mummified Thyroid Nodules

Figure 4

(a) A 53-year-old female had a thyroid nodule with clear margin and the maximum diameter of 21 mm. (b) Two years later, the nodule became smaller and more solid, the margin of the nodule was blurred, and the nodule was classified as TI-RADS 4. (c) CEUS showed that the edge of the nodule was slightly ring-shaped with low enhancement, while the interior of the nodule was uneven with low enhancement. (d) The contrast video was analyzed using SonoLiver software. (e, f) The time intensity curve and time-difference curve were obtained. It showed that the intensity of the whole nodule, its periphery, and its interior was always lower than those in the control area with time, and the intensity in the central area was the lowest, which was close to no enhancement.