Research Article
An Investigation on the Risk Factors of Thyroid Diseases in Community Population in Hainan
Table 9
Multivariate logistic regression analysis of the prevalence of thyroid diseases.
| Variables | β | S.E. | Wald | p | OR | 95%CI |
| Gender | Male (ref) | | | | | | | Female | 0.91 | 0.16 | 31.45 | <0.001 | 2.49 | 1.81–3.43 | Age | 18–29 (ref) | | | | <0.001 | | | 30–39 | 1.65 | 0.47 | 12.28 | 0.213 | 1.44 | 2.07–13.06 | 40–49 | 1.13 | 0.43 | 6.80 | <0.001 | 2.44 | 1.32–7.22 | 50–59 | 0.89 | 0.43 | 4.34 | 0.009 | 3.09 | 1.05–5.63 | 60–69 | 0.52 | 0.42 | 1.55 | 0.037 | 5.20 | 0.74–3.85 | ≥70 | 0.44 | 0.44 | 0.99 | 0.319 | 1.55 | 0.66–3.66 | BMI | 18.5 ≤ BMI < 2 (ref) | | | | 0.320 | | | BMI<18.5 | −0.30 | 0.40 | 0.57 | 0.452 | 0.74 | 0.34–1.63 | 24 ≤ BMI<28 | 0.19 | 0.28 | 0.44 | 0.506 | 1.20 | 0.70–2.08 | BIM ≥ 28 | −0.04 | 0.28 | 0.02 | 0.876 | 0.96 | 0.55–1.66 | Smoking | Yes (ref) | | | | | | | No | 0.24 | 0.24 | 0.93 | 0.335 | 1.27 | 0.78–2.04 | Region | Suburb (ref) | | | | | | | Urban | 0.07 | 0.17 | 0.15 | 0.696 | 1.07 | 0.77–1.48 | Season | Spring (ref) | | | 2.05 | 0.562 | | | Summer | −0.03 | 0.21 | 0.02 | 0.881 | 0.97 | 0.64–1.47 | Autumn | −0.26 | 0.21 | 1.63 | 0.201 | 0.77 | 0.51–1.15 | Winter | 0.07 | 0.24 | 0.08 | 0.777 | 1.07 | 0.66–1.73 | Family history of thyroid disease | Yes (ref) | | | | | | | No | −0.85 | 0.23 | 13.96 | <0.001 | 0.43 | 0.27–0.67 | Hyperlipidemia | Yes (ref) | | | | | | | No | −0.15 | 0.20 | 0.56 | 0.456 | 0.86 | 0.58–1.28 | Hyperuric acidemia | Yes (ref) | | | | | | | No | −0.01 | 0.17 | 0.00 | 0.968 | 0.99 | 0.71–1.39 | Hypertension | No (ref) | | | | | | | Yes | 0.15 | 0.18 | 0.68 | 0.409 | 1.16 | 0.82–1.65 | Gout disease | No (ref) | | | | | | | Yes | 0.13 | 0.23 | 0.33 | 0.567 | 1.14 | 0.72–1.81 | TPOAb | − (ref) | | | | | | | + | 0.43 | 0.22 | 3.74 | 0.053 | 1.54 | 0.99–2.38 | TgAb | − (ref) | | | | | | | + | −0.36 | 0.25 | 2.15 | 0.143 | 0.70 | 0.43–1.13 | Triglyceride | Normal (ref) | | | 2.38 | 0.304 | | | L | 0.26 | 0.43 | 0.36 | 0.547 | 1.30 | 0.56–3.00 | H | 0.24 | 0.16 | 2.20 | 0.138 | 1.27 | 0.92–1.75 | Total cholesterol | Normal (ref) | | | 0.15 | 0.926 | | | L | −0.09 | 1.07 | 0.01 | 0.934 | 0.92 | 0.11–7.41 | H | −0.06 | 0.16 | 0.15 | 0.699 | 0.94 | 0.69–1.29 | LDL | Normal (ref) | | | 0.91 | 0.635 | | | H | 0.17 | 0.18 | 0.86 | 0.354 | 1.18 | 0.83–1.68 | HDL | Normal (ref) | | | | | | | L | 0.51 | 0.63 | 0.65 | 0.420 | 1.66 | 0.49–5.67 | H | −0.08 | 0.16 | 0.21 | 0.647 | 0.93 | 0.67–1.28 | Serum vitamin D3 | Inadequate | | | | | | | Amplitude | 0.01 | 0.18 | 0.01 | 0.939 | 1.01 | 0.71–1.44 |
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TPOAb: thyroid peroxidase antibody; TgAb: thyroglobulin antibody; “+”: positive autoantibody; “−”: negative autoantibodies; LDL: low-density lipoprotein; HDL: high-density lipoprotein. “ ” and bold text represent statistical significance. “ ” and bold text represent statistical significance. |