International Journal of Endocrinology

Research Article

Occult Renal Calcifications in Patients with Normocalcemic Primary Hyperparathyroidism and Their Association with the Parathyroid Hormone-Vitamin D Axis

Table 2

Laboratory data in NPHPT patients with and without renal calcifications.


	Renal calcifications (urolithiasis/nephrocalcinosis)
Variable	N	Normal range	Present (N = 9)	Absent (N = 25)

Serum PTH (pg/mL)	34	15–65	137.00 (104.10; 249.90)	86.40 (81.15; 113.80)	0.001
Serum 25(OH)D (ng/mL)	34	30–60	37.20 ± 6.92	39.65 ± 9.53	0.571
Serum 1.25(OH)₂D (pg/mL)	17	18–72	96.83 ± 20.00 (20.65)	62.36 ± 21.24 (34.06)	0.005
Serum calcium (mg/dL)	34	8.4–10.4	9.69 ± 0.67	9.22 ± 0.57	0.052
Serum phosphate (mg/dL)	34	2.5–4.5	3.13 ± 0.38	3.57 ± 0.59	0.041
eGFR (mL/min/1.73 m²)	34	>60	91.11 ± 13.61	83.76 ± 12.68	0.153
Urinary calcium (mg/24 h)	34	<250	160.00 (122.50; 248.55)	116.00 (57.00; 183.50)	0.037
Urinary pH	34	5.5–7.5	6.62 ± 0.40	6.36 ± 0.51	0.195

Data are presented as mean ± SD or median (interquartile range). PTH, parathyroid hormone; 25OHD, 25-hydroxyvitamin D; 1.25(OH)₂D, 1.25-dihydroxyvitamin D.