Paeoniflorin Ameliorates Hyperprolactinemia-Induced Inhibition of Osteoblastogenesis by Suppressing the NF-κB Signaling Pathway

Scheme 1

PF ameliorated HPRL-induced osteoblastogenesis inhibition by promoting osteoblast differentiation by inhibiting nuclear factor kappa B (NF-κB) activity. PRL, prolactin; PRLR, prolactin receptor; ALP, alkaline phosphatase; OSX, Osterix; RUNX2, runt-related transcription factor 2; IκB-α, inhibitor of kappa B alpha.