Research Article

Pregnancy Status Is Associated with Lower Hemoglobin A1c among Nondiabetes Women in the United States from NHANES 2005–2016

Table 1

Weighted characteristics of the study sample with and without pregnancy in nondiabetes women.

Urine pregnancy positive (n = 592)Urine pregnancy negative (n = 7170) value

Average gestational period (months)5.58 ± 2.29Not available

Age (years)27.09 ± 5.8031.03 ± 9.96<0.001
Age groups<0.001
<2044 (7.43%)921 (12.85%)
≥20, <35478 (80.74%)3466 (48.34%)
≥3570 (11.82%)2783 (38.81%)
Body mass index (kg/m2)28.84 ± 6.6127.99 ± 7.480.007

Race (%)<0.001
Mexican American165 (27.87%)1458 (20.33%)
Other Hispanic44 (7.43%)640 (8.93%)
Non-Hispanic White217 (36.66%)2684 (37.43%)
Non-Hispanic Black110 (18.58%)1631 (22.75%)
Other races including multiracial56 (9.46%)757 (10.56%)

At least 12 alcoholic drinks in a lifetime (%)<0.001
Yes100 (16.89%)845 (11.79%)
No128 (21.62%)917 (12.79%)
Not available364 (61.49%)5408 (75.43%)

Smoked at least 100 cigarettes in life (%)<0.001
Yes156 (26.35%)2015 (28.10%)
No392 (66.22%)4231 (59.01%)
Not available44 (7.43%)924 (12.89%)<0.001

HbA1c (%)4.98 ± 0.365.26 ± 0.44<0.001
Serum glucose (mmol/L)4.67 ± 0.794.93 ± 0.86<0.001
Hemoglobin (g/dL)12.21 ± 1.1013.21 ± 1.20<0.001
Serum uric acid (µmol/L)224.21 ± 53.54266.86 ± 61.02<0.001
Alkaline phosphatase (U/L)78.52 ± 53.0267.25 ± 31.71<0.001
Blood urea nitrogen (mmol/L)2.34 ± 1.003.69 ± 1.28<0.001
Total cholesterol (mmol/L)5.74 ± 1.394.74 ± 0.94<0.001
Serum creatinine (µmol/L)50.44 ± 12.8864.33 ± 19.50<0.001
Serum phosphorus (mmol/L)1.29 ± 0.181.24 ± 0.19<0.001
Total protein (g/L)64.44 ± 4.9171.64 ± 4.29<0.001
Serum sodium (mmol/L)136.73 ± 1.87138.77 ± 1.87<0.001
Serum potassium (mmol/L)3.75 ± 0.253.88 ± 0.28<0.001
Platelet count (1000 cells/µL)253.80 ± 67.48274.70 ± 68.83<0.001

Notes: mean ± SD for continuous variables: P value was calculated by the weighted linear regression model. % for categorical variables: P value was calculated by the weighted chi-square test.