Sex Difference in the Association of Osteoporosis and Osteopenia Prevalence in Patients with Adrenal Adenoma and Different Degrees of Cortisol Excess

Table 3

Unadjusted odds ratio of associating factors for predicting osteoporosis and osteopenia in male and female patients.

	Total		MACS
	Men (n = 55); odds ratio (95% CI); value	Women (n = 182); odds ratio (95% CI); value	Men (n = 42); odds ratio (95% CI); value	Women (n = 99); odds ratio (95% CI); value
1 mg DST cortisol > 5.0 μg/dl	16.000; (1.902–134.580); 0.003	2.190; (1.038–4.619); 0.041	11.077; (1.201–102.193); 0.013	1.340; (0.583–3.084); 0.533
1 mg DST cortisol, μg/dl	1.150; (1.039–1.273); 0.007	1.092; (1.043–1.144); <0.001	1.221; (1.027–1.452); 0.032	1.092; (0.983–1.213); 0.100
Cushingoid features	6.343; (1.509–26.656); 0.014	2.701; (1.472–4.958); 0.002	ND	ND
Age, years	0.993; (0.947–1.041); 0.771	1.004; (0.983–1.026); 0.705	1.009; (0.949–1.073); 0.784	1.044; (1.006–1.084); 0.024
BMI, kg/m^2	0.948; (0.816–1.101); 0.484	0.946; (0.886–1.011); 0.103	0.945; (0.771–1.159); 0.588	0.974; (0.898–1.058); 0.537

All values <0.05 were considered statistically significant. BMI,, body mass index; CI, confidential interval; DST, overnight dexamethasone suppression test; MACS, mild autonomous cortisol secretion; ND, not determined.