Sex Difference in the Association of Osteoporosis and Osteopenia Prevalence in Patients with Adrenal Adenoma and Different Degrees of Cortisol Excess

Table 5

Receiver operator characteristic curve analysis for predicting osteoporosis and osteopenia by continuous valuables of 1 mg dexamethasone suppression test cortisol levels.

	Sex	Optimal cutoff value, μg/dl (Sen, Spe)	AUC ± SE (95% CI)	value
Total	Men (n = 55)	9.4 (0.692, 0.762)	0.780 ± 0.069 (0.644–0.916)	<0.001
	Women (n = 182)	12.6 (0.586, 0.771)	0.665 ± 0.041 (0.585–0.745)	<0.001
MACS	Men (n = 42)	7.5 (0.857, 0.811)	0.801 ± 0.098 (0.610–0.992)	0.012
	Women (n = 99)	6.5 (0.535, 0.571)	0.580 ± 0.058 (0.466–0.693)	0.170

All values <0.05 were considered statistically significant. AUC, area under the curve; CI, confidential interval; MACS, mild autonomous cortisol secretion; SE, standard error; Sen, sensitivity; Spe, specificity.