ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway

Figure 2

ASPM depletion inhibits proliferation, migration, and invasion of ATC cells. ((a), (b)) Validation of ASPM knockdown in 8505C and TTA1 cells by qRT-PCR and western blotting. ((c), (d)) ATC cell proliferation was evaluated by CCK-8 assay and colony formation assay. ((e), (f)) Migration and invasion abilities of ATC cells were assessed by Transwell assay. (g) The protein levels of E-cadherin, N-cadherin, and vimentin in ATC cells after transfection of sh-ASPM. , .

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