Somatostatin Treatment for Ectopic ACTH Syndrome due to Pancreatic Neuroendocrine Tumors: Review of the Literature

Figure 2

Pathology and immunochemistry staining of tumors of the pancreas (a, b, e, and f) and liver metastasis (c, d, and g). (a) Pancreatic neuroendocrine tumor (hematoxylin and eosin staining, magnification ×200); (b) the percentage of Ki-67-positive cells (brown color) was 15% in the pancreatic tumor (magnification ×200); (c) liver metastases of the neuroendocrine tumor (hematoxylin and eosin staining, magnification ×200); (d) the percentage of Ki-67-positive cells (brown color) was 10% in the hepatic metastases (magnification ×200); (e) positive immunostaining for CRH (brown color) in the liver metastasis (magnification ×200); (f) & (g) positive immunostaining for SSTR2 (brown color) in the pancreatic tumor (magnification ×400) (f) and in the hepatic metastases (magnification ×400) (g).

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