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Year | First author | Age at diagnosis (year) | Sex | Morning ACTH (pg/ml) | Morning cortisol (ug/dl) | 24 h UFC (ug/d) | Pancreatic tumor size (cm) | Tumor metastasis | Percentage of Ki-67 | Treatment procedure | Effect of controlling ACTH and cortisol after SSA treatment | Effect of tumor growth after SSA treatment | Duration of follow-up (months) | Prognosis |
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2020 | Our case | 23 | F | 139 | 24.1 | 653.64 | 1.1 × 0.8 | Lymph nodes and multiple liver metastases | 10–15% | Octreotide LAR and operation | Controlled | SD | 28 | Survival |
2017 | do Amor Divino et al. [14] | 58 | M | 190 | 48 | 6519 | 5.0 | Multiple liver metastases | 6% | Operation, octreotide LAR and chemotherapy | Uncontrolled | PD | 42 | N/A |
2016 | Tadokoro et al. [15] | 61 | F | 205.9 | 15.2 | 86.1 | 6.0 | Lymph nodes metastasis | 11.50% | Octreotide LAR and chemotherapy | Uncontrolled | PD | 36 | Died |
2014 | Sauer et al. [16] | 46 | M | 247 | 1198 | 38200 | 1.2 | Liver metastasis | <1% | Octreotide and operation | N/A | N/A | N/A | N/A |
2014 | Rajeev et al. [17] | 34 | M | 227 | 72.6 | N/A | N/A | Lymph nodes and liver metastasis | 20% | Operation, lanreotide, and sunitinib | Uncontrolled | PD | 27 | Survival |
2013 | Patel et al. [18] | 44 | F | N/A | N/A | N/A | Large | Multiple liver metastases | N/A | Operation and octreotide LAR | Controlled | N/A | 74 | N/A |
2010 | Kondo et al. [19] | 64 | F | 340 | 26.9 | 893 | 2.5 × 2.5 | Multiple liver metastases | 10% | Octreotide LAR and operation | Controlled | PR | 20 | Survival |
2003 | Doi et al. [20] | 21 | F | 735 | 145 | N/A | 5.0 × 3.5 × 2.0 | Liver and lymph nodes metastasis | N/A | Octreotide and operation | Controlled | PD | 61 | Died |
1999 | Gill et al. [21] | 31 | F | 177 | 78.2 | 2102 | N/A | Liver, bone, and pelvic metastasis | N/A | Octreotide and operation | Controlled | PD | 18 | Died |
1993 | Woodhouse et al. [22] | 33 | F | 436 | 181.2 | N/A | N/A | Extensive liver metastasis | N/A | Operation and octreotide | Controlled | PR | 18 | N/A |
1989 | Bertagna et al. [23] | 37 | F | 218 | 26 | 550 | N/A | Diffuse metastasis | N/A | Chemotherapy and octreotide | Controlled | PD | 4 | Died |
1988 | Lamberts et al. [24] | 37 | M | 68.1 | 32 | 1080 | 5.0 × 3.0 | Lymph nodes metastasis | N/A | SMS 201-995 | Controlled | PR | 6 | N/A |
1988 | Ruszniewski et al. [25] | 49 | F | 138 | 16.5 | N/A | N/A | Multiple liver metastases | N/A | Operation, chemotherapy, and SMS 201-995 | Controlled | SD | 80 | N/A |
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