Correlation between Maternal Vitamin D and Thyroid Function in Pregnancy with Maternal and Neonatal Outcomes: A Cross-Sectional Study
Table 1
Studied population characteristics in different trimesters.
First trimester
Second trimester
Third trimester
Age, mean ± SD, years
28.04 ± 4.31
28.04 ± 5.21
29.21 ± 4.52
0.688
Vitamin D levels, mean ± SD, ng/ml
29.21 ± 4.53
28.05 ± 5.21
28.05 ± 4.31
0.381
Vitamin D status, n (%), ng/ml
Severe vitamin D deficiency
1 (4.55)
0 (0)
0 (0)
0.573
Moderate vitamin D deficiency
6 (27.27)
7 (31.81)
5 (22.72)
Mild vitamin D deficiency
5 (22.74)
4 (18.18)
2 (9.09)
Normal
10 (45.45)
11 (50)
15 (68.1)
T3, median (IQR), mg/ml
15.38 (4.07–28.52)
12.33 (1.23–13.32)
14.39 (10.43–17.55)
0.088
T4, median (IQR), mg/ml
4.95 (4.27–5.28)
4.05(3.4–4.5)
4.25(4.03–4.46)
0.074
TSH, median (IQR), mIU/L
2.58 (0.58–3.64)
1.59 (0.57–3.13)
3.41 (1.38–5.12)
0.979
Thyroid function, n (%)
Hyperthyroidism
1 (4.54)
1 (4.54)
4 (18.18)
0.305
Euthyroid
16 (72.72)
20 (90.90)
14 (63.63)
Subclinical hypothyroidism
4 (18.18)
0 (0)
3 (13.63)
Hypothyroidism
1 (4.54)
1 (4.54)
1 (4.54)
A value of less than 0.05 is considered significant. Normally distributed variables are shown as mean ± SD. Nonparametric variables are shown as median (IQR). IQR, interquartile range; n, number; TSH thyroid-stimulating hormone.