Research Article

Association between Serum Cotinine Levels and Bone Mineral Density: An Analysis of the National Health and Nutrition Examination Survey (NHANES)

Table 1

Weighted characteristics of study participants.

CharacteristicsMen (n = 3945)Women (n = 3960) value

Age (years)45.03 ± 0.1845.41 ± 0.190.069
Race/ethnicity (%)0.004
 Mexican American10.33 ± 0.029.03 ± 0.01
 Non-Hispanic black10.10 ± 0.0112.03 ± 0.01
 Non-Hispanic white63.52 ± 0.0262.84 ± 0.02
 Other race/ethnicity16.04 ± 0.0116.18 ± 0.01
Education level (%)0.003
 ≤ high school22.91 ± 0.0118.85 ± 0.01
 > high school77.09 ± 0.0181.15 ± 0.01
Body mass index (kg/m2)29.45 ± 0.1629.83 ± 0.210.088
Moderate activities (%)<0.001
 Yes34.20 ± 0.0114.63 ± 0.01
 No65.80 ± 0.0185.27 ± 0.01
Serum albumin (g/L)43.70 ± 0.0141.85 ± 0.10<0.001
Blood urea nitrogen (mg/dL)5.02 ± 0.044.38 ± 0.04<0.001
Serum uric acid (mg/dL)6.03 ± 0.034.66 ± 0.02<0.001
Serum phosphorus (mg/dL)1.17 ± 01.12 ± 0<0.001
Serum calcium (mg/dL)9.38 ± 0.019.30 ± 0.01<0.001
Lumbar BMD (mg/cm2)1031.60 ± 3.271035.46 ± 3.72<0.001
Serum cotinine (ng/L)82.55 ± 4.4049.65 ± 3.05<0.001

Data are expressed as weighted proportions (± standard error (SE)) for categorical variables and as weighted mean ± SE for continuous variables. Weighted two-tailed t tests and weighted Rao-Scott chi-square test were used to compare difference between groups.