Review Article
The Prevalence and Characteristics of Exocrine Pancreatic Insufficiency in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Table 1
Study and patient characteristics of the included studies.
| | Study | Region | Total patients (n) | Age, y | Duration of diabetes | Insulin use (%) | Methods | Total EPI (n) | Severe EPI (n) |
| | Larger 2012 | Europe | 472 | 59 (52–67) | 11 (5–15) | 60 | FE-1 | 85 | 50 | | Aksoz 2020 | Asia | 57 | 51 (27–59) | 12 (7–28) | 57.9 | FE-1 | 28 | 15 | | Kumar 2018 | Asia | 88 | 47.53 ± 8.9 | NA | NA | FE-1 | 72 | 30 | | Čabarkapa 2018 | Europe | 62 | 61.1 ± 8.9 | 16.1 ± 8.9 | NA | FE-1 | 13 | 3 | | Hardt 2003 | Europe | 697 | 53.8 (21–78) | 8.7 (<1–39) | 52.5 | FE-1 | 247 | 139 | | Shivaprasad 2015 | Asia | 95 | 50.2 ± 10.2 | NA | NA | FE-1 | 28 | 3 | | Søfteland 2019 | Europe | 52 | NA | NA | NA | FE-1 | 3 | NA | | Terzin 2014 | Europe | 101 | 60.9 ± 11.2 | 11.2 ± 8.8 | 61.4 | FE-1 | 17 | 3 | | Vujasinovic 2013 | Europe | 100 | NA | NA | 50 | FE-1 | 5 | 3 | | Nunes 2003 | Europe | 42 | 62 ± 10 | 11.5 ± 8 | 28.6 | FE-1 | 15 | 9 | | Riceman 2019 | Australia | 109 | 40–80 | NA | NA | FE-1 | 10 | 4 | | Lv 2021 | Asia | 85 | 61.4 ± 12.3 | 7 (7) | 49.4 | FE-1 | 16 | 3 | | Anoop 2021 | Asia | 118 | 56.1 ± 8.4 | 12.3 ± 6.2 | 22.9 | 72 h FF | 53 | NA |
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Data are expressed as median, mean (SD), or range. NA: not applicable; 72 h FF: 72-hours fecal fat. |
