Clinical Implications of Age in Differentiated Thyroid Cancer: Comparison of Clinical Outcomes between Children and Young Adults
Table 4
Subanalysis of clinicopathological characteristics in pediatric subgroups.
≤16 years (n = 37)
17–19 years (n = 61)
value
Age (years)
13.9 ± 3.1
18.4 ± 0.8
<0.001
Male : female
1 : 4.3
1 : 14.3
<0.001
Male
7 (18.9%)
4 (6.6%)
Female
30 (81.1%)
57 (93.4%)
Tumor size (cm)
2.3 ± 1.0
1.9 ± 1.5
0.205
Type of carcinoma
0.184
PTC
36 (97.3%)
55 (90.2%)
FTC
1 (2.7%)
6 (9.8%)
Multifocality
10 (27.0%)
14 (23.0%)
0.809
Bilaterality
8 (21.6%)
7 (11.5%)
0.247
ETE
19 (51.4%)
17 (27.9%)
0.007
T stage
0.012
T1
10 (27.0%)
34 (55.7%)
T2
8 (21.6%)
9 (14.8%)
T3
16 (43.2%)
17 (27.9%)
T4
3 (8.1%)
1 (1.6%)
N stage
<0.001
N0
7 (18.9%)
18 (29.5%)
N1a
10 (27.0%)
33 (54.1%)
N1b
20 (54.1%)
10 (16.4%)
M stage
0.718
M1
1 (2.7%)
1 (1.6%)
Recurrence
6 (16.2%)
8 (13.1%)
0.564
Data are expressed as patient’s number (%) or mean ± SD. A statistically significant difference was defined as . PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; ETE, extrathyroidal extension; T, tumor; N, node; M, metastasis.
